United States Pharmacopeia research study confirms lack of triterpenes and beta-glucans in many Reishi products
In August, 2017, Nature, the worlds most cited scientific journal, published in its Scientific Reports an important analytical study about Reishi mushroom products. United States Pharmacopeial Convention (USP) sponsored this project with a leading mushroom scientist from China, Dr. Li Shao-ping. In their research, 19 different Reishi mushroom products sold in the USA were tested for the compounds that characterize a real Reishi mushroom (fruiting body). They used scientifically identified and validated Reishi mushrooms as their standard.
In the USP study, they utilized various highly accurate testing methods including HPTLC, Colorimetric method, GC-MS, and High Performance Size-exclusion Chromatography. The results of their study demonstrated clearly that only 5 of 19 samples could be verified as genuine Reishi mushroom. Most of the other products lacked characteristic triterpenoids and also had a starch-like polysaccharide profile that was inconsistent with Reishi mushroom.
During the study, Jeff Chilton, founder of Nammex, was in contact with USP and alerted the researchers to quality control issues including mycelium products that are grown on grain. Many of the samples they had purchased, which were sold and labeled as mushroom, were in fact mycelium on grain. More importantly, because of his long-standing work with mushrooms, Jeff was allowed to submit some Nammex Reishi mushroom extract samples.
USP made the following statement in the abstract of their research.
“ The results showed that the measured ingredients of only 5 tested samples (26.3%) were in accordance with their labels, which suggested the quality consistency of G. lucidum dietary supplements in the U.S. market was poor, which should be carefully investigated.”
3 out of the 5 samples (60%) that passed USP’s testing standards were Nammex reishi mushroom extracts.
The USP research has now confirmed what Jeff Chilton has demonstrated in his published 2015 White Paper, Redefining Medicinal Mushrooms, and his presentation to the International Society for Mushroom Science symposium in 2016.
Nammex commends USP for initiating this study and assisting the health and wellness industry with the validation of quality standards for mushroom products.
USP Research Article: https://www.nature.com/articles/s41598-017-06336-3 (Nature Scientific Reports 7, Article number: 7792(2017)